" HIDDEN SEPSIS."

Hidden Sepsis in the Palatine Tonsils

we get indications of its location and nature. We spend much of our time in looking for foci of infection, and their discovery and eradication often bring most gratifying results; conversely, overlooked foci produce many of the tragic and irreparable conditions that we frequently see in general practice. I refer to advanced cases of arthritis, cardiovascular disease, and patients with general d...

Dog bites: hidden danger of fulminant sepsis.

Dog bites are a common problem in family practice. Although the summer months often show a seasonal increase in the number of bites seen, they can and do occur at any time during the year. Often the family pet, not a stray animal, inflicts the bite. Because many dog owners have their pets vaccinated and know whether their pet has been exposed to rabies, victims bitten by the family dog are like...

Modeling sepsis progression using hidden Markov models

Characterizing a patient’s progression through stages of sepsis is critical for enabling risk stratification and adaptive, personalized treatment. However, commonly used sepsis diagnostic criteria fail to account for significant underlying heterogeneity, both between patients as well as over time in a single patient. We introduce a hidden Markov model of sepsis progression that explicitly accou...

The hidden sepsis marker: aPTT waveform analysis.

Thromb Haemost 2008; 100: 9–10 Downey et al. published a paper in 1997 entitled ‘Novel and diagnostically applicable information from optical waveform analysis of blood coagulation in disseminated intravascular coagulation’ (1). Using a new automated coagulation analyzer, the MDA-180, the authors observed that during measurement of the aPTT, some samples became turbid immediately after addition...

The lingering consequences of sepsis: a hidden public health disaster?